After searching for something natural that specifically enhances serotonin levels, besides good diet, yoga/exercise/sauna I can confidently say this...
36 people found this helpful

We only use clinically researched ingredients backed by science.* Every formula is crafted with pure, high-quality nutrients at effective doses designed for safety, potency, and real results you can trust.*
Clinical studies in healthy adultsaffron® saffron extract has been shown in human trials to help support mood and emotional well-being.*
Clinical research in adolescentsControlled research shows saffron extract can help encourage calmness and balanced mood in youth.*
Studied in older adultsResearch shows curcumin supplementation supports cognitive performance and healthy mood in aging populations.
Clinical study in adultsA published trial found curcumin supported memory, attention, and overall brain health in non-demented adults.
Human & animal researchStudies suggest maintaining healthy zinc levels plays a role in emotional balance and calmness.*
Happy Brain, Healthy Body*
Happy Saffron Plus® isn’t just doctor-developed, it's doctor-recommended, loved in 217 countries, and backed by over 25 human studies.*
In the largest clinical trial on saffron and mood to date, 72% of participants taking affron® (the exact extract in this formula) experienced meaningful mood improvement, many in just 5 weeks.*
With Longvida® curcumin for focus and memory, plus zinc glycinate for mood and sexual health, this 3-in-1 formula delivers fast, feel-good results - naturally.*
Healthier, Happier YOU*
Supports mood, memory, stress, sleep, and libido with three clinically studied ingredients.*
A synergistic, highly absorbable formula for better results—without hormones or SSRIs.*
Day 1 - Instant Memory Boost
Clinical research shows that 400 mg of Longvida® curcumin—the same amount used in Happy Saffron Plus®—can boost working memory by 16% within just one hour of your first dose.*
Week 4 - Sweet Dreams & Bright Moods
In just 4 weeks, 28 mg/day of affron® saffron helped improve mood and sleep, and reduced stress by 41% in clinical trials.*
Week 12 - More Happiness, Less Anxiousness
In 12 weeks, 28 mg/day of affron® saffron significantly improved mental health, reduced occasional anxiousness by 33% and low mood by 32%.*
Long-Term - Cumulative Brain & Body Benefits
Expect better mood, memory, and sexual health with continued use.*
It’s recommended that adults take 3 capsules daily between meals.*
Children ages 4-18 years can take 1 capsule per 40 pounds body weight, maximum 3 capsules daily.*
Yes. Happy Saffron Plus® is suitable for vegans, especially those seeking to improve their mood.*
As with other BrainMD products, this is a dietary supplement, not a drug.* It isn’t habit-forming.*
It is free from dairy, gluten, sugar, corn, nuts, eggs, yeast, and artificial flavorings or colorings.* It does contain very small levels of soy (non-GMO).*
After searching for something natural that specifically enhances serotonin levels, besides good diet, yoga/exercise/sauna I can confidently say this...
36 people found this helpful
We were going through a tough time after losing our dog and needed a little extra support. I took this daily for the entire bottle and genuinely...
6 people found this helpful
This was recommended to me by a nutritionist in conjunction with some other vitamins but honestly, I feel happier and have a little bit more energy...
6 people found this helpful
These saved my life, literally! Depression is not only a chemical imbalance, it is also a wiring issue. I am lucky to be alive, and I tribute that to...
15 people found this helpful
You will definitely feel a difference in your mood and anxiety levels in a couple of weeks.
6 people found this helpful
We like Dr. Amen's stuff. Very high quality and good potency. However, buyer beware on any type of supplement. Saffron increases many things in your...
60 people found this helpful
This stuff is amazing!! Helps with my depression.
13 people found this helpful
These have been great post pregnancy! Just be careful not to use if breastfeeding!
You can completely trust Dr. Amen and his products. Everything is well researched and formulated.
3 people found this helpful
Total life and game changer. It’s been over a year now and I will never stop taking this stuff. My mood has improved, metal health is so much better,...
32 people found this helpful
This product truly is wonderful. Dr. Eamon never disappoints.
4 people found this helpful
These do seem to help lift your mood!
1 people found this helpful
Wow! I've been taking for a month. My head feels clearer, memory is better and I sleep better at night. I highly respect Dr Amen and think this is a...
8 people found this helpful
Took these as directed for 2 weeks. Made me have the strangest head/pressure in the front and on the sides on my temple for little one 3 weeks....
3 people found this helpful
This has been a game changer for me. I don’t think I’ve ever left an Amazon review before but this has made a noticeable impact on my mood. I’m...
2 people found this helpful
So far so good. I do believe it’s helping me.
6 people found this helpful
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